CJC-1295 vs Ipamorelin — how these two somatotropic-axis research peptides compare by receptor target and research focus. Research Use Only.
CJC-1295 vs Ipamorelin at a glance
| CJC-1295 (No DAC) | Ipamorelin | |
|---|---|---|
| Class / mechanism | GHRH-receptor analog (Modified GRF 1-29) | Selective ghrelin-receptor (GHSR-1a) agonist |
| Sequence | Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| CAS number | 863288-34-0 | 170851-70-4 |
| Research focus | GHRH-receptor binding, somatotropic-axis signaling | Ghrelin-receptor binding, growth-hormone secretagogue mechanism |
| Form | Lyophilized powder | Lyophilized powder |
| Storage | -20°C, protected from light | -20°C, protected from light |
What’s the difference?
CJC-1295 and Ipamorelin act on two different receptors of the somatotropic axis: CJC-1295 on the GHRH receptor and Ipamorelin on the ghrelin (GHSR-1a) receptor. Because these pathways are complementary, the two are frequently studied together, as in the CJC-1295 + Ipamorelin blend.
Which to use in research
Select by the receptor of interest: CJC-1295 for GHRH-receptor questions and Ipamorelin for ghrelin-receptor questions. Many study designs examine them in combination. Both are supplied lyophilised and reconstituted the same way.
Handling
All are supplied as lyophilised powder for reconstitution in bacteriostatic or sterile water. See the reconstitution guide and calculator. Each lot ships with a lot-specific Certificate of Analysis.
Learn more
Read the individual overviews: CJC-1295 (No DAC) research overview · Ipamorelin research overview.
Buy for research
Frequently asked questions
Are CJC-1295 and Ipamorelin the same?
No. CJC-1295 is a GHRH-receptor analog and Ipamorelin is a selective ghrelin-receptor (GHSR-1a) agonist; they act on different receptors of the somatotropic axis.
Why are CJC-1295 and Ipamorelin combined?
Because their receptor pathways are complementary, they are commonly studied together — available as the CJC-1295 + Ipamorelin blend.
Part of our research peptides handbook.